Caffey-Silverman Syndrome in a Young Infant: Case Reportand Literature Review
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Abstract
Infantile cortical hyperostosis (ICH), also known as Caffey-Silverman syndrome, is a rare, self-limiting inflammatory bone disease affecting infants under six months of age. We report the case of a five-month-old female infant presenting with fever, irritability, and tibial swelling, initially misdiagnosed as an infection. The definitive diagnosis was confirmed through radiological studies and magnetic resonance imaging. The patient showed favorable clinical evolution with supportive treatment. This report discusses the main clinical, radiological, and genetic features described in the literature and highlights the importance of differential diagnosis. Early recognition of ICH prevents unnecessary treatments, invasive procedures, and misdiagnosis of child abuse.
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